Browsing Department of Phamacy by Title

Now showing items 11-12 of 12

Virtual screening for chemical analogues similar to phytochemicals that inhibit aldose reductase in the development of diabetic microvascular complications

Otieno, Filex; Kagia, Richard (F1OOO research, 2023-03-21)

Background: The polyol pathway contributes to the development of diabetic complications but can be inhibited by plant phytochemicals. This study aimed at assessing analogs of specific flavonoids that delay onset of ...
Virtual screening of zinc compounds similar to NSAIDS with better pharmacodynamic and pharmacokinetic profiles

Kamakia, Faith; Ouma, Stephen; Kagia, Richard (F1OOO research, 2023-04-26)

BACKGROUND: Pain is a common symptom that is managed in both outpatients and inpatients. There are many side effects associated with opioids such as respiratory depression, constipation, hyperalgesia, and tolerance. ...