Diosgenin is a natural steroid sourced from plants and exhibits good analgesic and anti-inflammatory activity. However, mechanism of action associated with the analgesic activity of diosgenin is not yet delineated. Hence, ...

and is spread through the air. Multidrug-resistant tuberculosis (MDR TB) has become a global health concern. This study focuses on developing alternative compounds to Levofloxacin, Moxifloxacin, Bedaquiline, Kanamycin, ...

Introduction: Paracetamol is the most used drug for the management of pain and as an antipyretic through its mechanism of action on Cox 1,2 and 3 receptors. Paracetamol is a lipid-soluble molecule that can pass through ...

Introduction: Use of natural products for management of diseases has increased widely due to the belief that natural products are less toxic than conventional medicines. Natural products have been utilised for management ...

Various members of the genus Vernonia are commonly used in traditional medicine to treat fever, malaria, diarrhoea, dysentery, hepatitis, cough, fertility inducer and as a laxative. Vernonia myrianthum (Gymnanthemum myrianthum) ...

BACKGROUND: Pain is a common symptom that is managed in both outpatients and inpatients. There are many side effects associated with opioids such as respiratory depression, constipation, hyperalgesia, and tolerance. ...

Background: The polyol pathway contributes to the development of diabetic complications but can be inhibited by plant phytochemicals. This study aimed at assessing analogs of specific flavonoids that delay onset of ...

Malaria remains one of the most fatal diseases caused by plasmodium parasites in Sub-Saharan Africa. The disease is characterized by symptoms and resemble the flu, including fever, headache, vomiting, and among others. ...