Browsing by Author "Kamakia, Faith"
Now showing items 1-4 of 4
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Determination of pharmacological activity of bioactives in Allium sativum using computational analysis
(F1OOO research, 2023-02)Introduction: Use of natural products for management of diseases has increased widely due to the belief that natural products are less toxic than conventional medicines. Natural products have been utilised for management ... -
In Silico Screening of Compounds Similar to Codeine, Tramadol, and Morphine with Better Pharmacodynamic and Pharmacokinetics Profiles
(Austin Journal of Pharmacology and Therapeutics, 2024-01-12)Pain alleviation is the primary intervention in promoting quality of life. Among the compounds used in management of pain are opioids. Codeine is mostly used as antitussive and is commonly present in cough syrups. Tramadol ... -
Pharmacokinetic and pharmacodynamic profiling of compounds similar to paracetamol from zinc database: an in silico analysis
(F1OOO research, 2023-06-21)Introduction: Paracetamol is the most used drug for the management of pain and as an antipyretic through its mechanism of action on Cox 1,2 and 3 receptors. Paracetamol is a lipid-soluble molecule that can pass through ... -
Virtual screening of zinc compounds similar to NSAIDS with better pharmacodynamic and pharmacokinetic profiles
(F1OOO research, 2023-04-26)BACKGROUND: Pain is a common symptom that is managed in both outpatients and inpatients. There are many side effects associated with opioids such as respiratory depression, constipation, hyperalgesia, and tolerance. ...
