Browsing by Author "Kagia, Richard"
Now showing items 1-8 of 8
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Antimalarial Usage and Associated Symptoms Among Malaria Patients Seeking Treatment at Makongeni Health Centre, Homa Bay County, Kenya
(AFRICAN JOURNAL OF MEDICAL BIOSCIENCES, 2023-05-11)Malaria remains one of the most fatal diseases caused by plasmodium parasites in Sub-Saharan Africa. The disease is characterized by symptoms and resemble the flu, including fever, headache, vomiting, and among others. ... -
Determination of pharmacological activity of bioactives in Allium sativum using computational analysis
(F1OOO research, 2023-02)Introduction: Use of natural products for management of diseases has increased widely due to the belief that natural products are less toxic than conventional medicines. Natural products have been utilised for management ... -
Identification of potential compounds for the management of multidrug-resistant tuberculosis using computational methods
(F1OOO research, 2023-03-20)and is spread through the air. Multidrug-resistant tuberculosis (MDR TB) has become a global health concern. This study focuses on developing alternative compounds to Levofloxacin, Moxifloxacin, Bedaquiline, Kanamycin, ... -
In Silico Screening of Compounds Similar to Codeine, Tramadol, and Morphine with Better Pharmacodynamic and Pharmacokinetics Profiles
(Austin Journal of Pharmacology and Therapeutics, 2024-01-12)Pain alleviation is the primary intervention in promoting quality of life. Among the compounds used in management of pain are opioids. Codeine is mostly used as antitussive and is commonly present in cough syrups. Tramadol ... -
In vitro Antimicrobial Activities, Qualitative Phytochemical Screening, and Free Radical Scavenging Capacities of Gymnanthemum myrianthum
(European Journal of Pharmaceutical Research, 2023-06-05)Various members of the genus Vernonia are commonly used in traditional medicine to treat fever, malaria, diarrhoea, dysentery, hepatitis, cough, fertility inducer and as a laxative. Vernonia myrianthum (Gymnanthemum myrianthum) ... -
Pharmacokinetic and pharmacodynamic profiling of compounds similar to paracetamol from zinc database: an in silico analysis
(F1OOO research, 2023-06-21)Introduction: Paracetamol is the most used drug for the management of pain and as an antipyretic through its mechanism of action on Cox 1,2 and 3 receptors. Paracetamol is a lipid-soluble molecule that can pass through ... -
Virtual screening for chemical analogues similar to phytochemicals that inhibit aldose reductase in the development of diabetic microvascular complications
(F1OOO research, 2023-03-21)Background: The polyol pathway contributes to the development of diabetic complications but can be inhibited by plant phytochemicals. This study aimed at assessing analogs of specific flavonoids that delay onset of ... -
Virtual screening of zinc compounds similar to NSAIDS with better pharmacodynamic and pharmacokinetic profiles
(F1OOO research, 2023-04-26)BACKGROUND: Pain is a common symptom that is managed in both outpatients and inpatients. There are many side effects associated with opioids such as respiratory depression, constipation, hyperalgesia, and tolerance. ...
